跳至主要内容

Predict diseases, intestinal microbes are more accurate

   Human diseases are affected by both genetic factors and environmental factors.

  Genetic factors, as we all know, are hidden in the genome. It can be known by sequencing the genome.

  When it comes to environmental factors, it is complicated, including age, diet, lifestyle (such as smoking, staying up late, etc.), living environment (such as rural or urban), and even the usual medications. How to measure all this?

  There is a direct and easy way, and that is to look at your gut microbiota. The influence of any environmental factor can eventually be reflected in the gut microbiota. For example, smokers and non-smokers, people living in rural areas and people living in cities, have different composition of gut microbiota. These microorganisms include bacteria, viruses, and fungi that are parasitic in the intestinal tract. The so-called "different composition" refers to the different types of intestinal microorganisms, the proportion of a certain type, etc.

  Don’t underestimate the information given to us by intestinal microbes. Recently, a foreign research team investigated 20 diseases that are affected by both genetic and environmental factors, including schizophrenia, Parkinson’s disease, hypertension, asthma, diabetes, and obesity. They found that changes in the intestinal microbiota can better reflect whether a person is likely to suffer from a certain disease than genes. Only type 1 diabetes is an exception.

  Why is this so? One possible reason is that the genome is "dead". For example, it is detected that you have an obesity gene, but when and under what circumstances this gene will work, genetic testing cannot tell you. The microbiome is "alive", it can capture changes in all aspects of your life anytime, anywhere. Also, in some cases, the altered gut microbiota can directly cause disease. For example, it has been found that at least three types of intestinal bacteria can cause colon cancer.

  Therefore, in the future, we only need to monitor the intestinal ecosystem to help diagnose or even prevent certain diseases. The monitoring method is also quite simple, which is to sequence the microorganisms in the stool sample. In foreign countries, many biological companies have begun to provide such services.


评论

此博客中的热门博文

Moroccan football team: "The most familiar stranger"

   When I was still in college ten years ago, I led a sightseeing group of more than 30 Moroccan students. Before meeting them, my general impression of the Moroccans was that they are from North Africa but closer to the Arab world. They have religious beliefs, are used to worship, and are inextricably linked with France.   When I saw the real person, I realized that the North Africans in front of me were actually a group of children playing with each other and having fun in time. They were about the same age as me at the time. I have all kinds of nicknames and nicknames. During the process of taking them to Badaling, the Summer Palace and Houhai, two classmates and I, together with more than 30 Moroccan students, realized "cultural integration" and "world unity" in the small group to some extent.   During the World Cup in Qatar, I was surprised to find that the little-known Morocco team, which was eliminated in the group stage of the last World Cup, after miraculou

Zeigarnik effect

  As a freelancer, you have to fight procrastination every day. "I've made up my mind many times, but I just can't change it. Is it because I'm slow or slow?". In fact, many procrastinations are irrational. Many obstructions are imagined by myself. So distract, postpone, avoid confrontation. It's cool to procrastinate, and it's cool to procrastinate all the time, so I can't do it. Concentration is also related to physical strength. When the physical strength is exhausted, it is even more difficult to concentrate. You’ll tell yourself: I’m too tired to do this—okay, another perfect procrastination.   In 1927, Bruma Zeigarnik's senior research found that people are more likely to care about unfinished and interrupted work than completed work. This is the Zeigarnik effect. For example, we often don't care much about what we have got, but we will especially cherish what we have worked hard but haven't got. Therefore, the TV series will tell you

Hebei Xingang Pharmaceutical Co., Ltd.

Hebei Xingang Pharmaceutical Co., Ltd is located in the industrial park of Zhao County, Shijiazhuang, Hebei, near the world-famous ZhaoZhou Bridge. Our facility neighbors the Qinyin Expressway and 308 National Highway on the east, and it neighbors the Jingzhu Expressway and 107 National Highway on the west. It is located 30 km from Shijiazhuang High-speed Train Station and 50 km from Shijiazhuang International Airport. Our company mainly focuses on the research, production and retail of rifamycin and its derivatives, and pharmaceutical raw materials and intermediates. Our products mainly include, Rifamycin S Sodium, Rifamycin S, 3-Formyl Rifamycin SV, Rifamycin SV Sodium, Rifampicin, Rifandine, Rifaximin, Rifapentine, Rifabutin, Rilmenidine, and so on. We are currently the world’s main manufacturer of anti-tuberculosis drugs and rifamycin and its derivatives. Hebei Xingang Pharmaceutical Co., Ltd was established in 1996. Upon establishment, the company had a clear developmental goal o